Giovanni Stefano (Brandizzi Lab)
Date & Location: September 26, 2017, at 12p; Room 168 Plant Biology
Subject: Novel players in plant endocytosis
Seminar Summary: Eukaryotic cells, through the endocytic process, internalize an equivalent of one to five times per hour their cell surface. In order to support this massive mechanism the endocytic recycling pathway must be precisely and finely regulated to maintain a perfect homeostasis at the plasma membrane. To date it is still unknown, where and how exactly endocytic clathrin-mediated events starts at plasma membrane level. It is well known that clathrin-coated vesicles (CCV) are necessary to start the endocytic process. However, in plant cells little is known about all the molecular mechanisms and accessory proteins involved in this process.
Here, I will present the role of two novel proteins in clathrin-mediated endocytosis and propose a new model that describes the establishment of specific areas of the PM where endocytosis events start.