- Mar 25, 2019
Date & Location: March 25, 2019, at 4p; Room 101 Biochemistry Building
Subject: Exploring the complex relationships between chromatin accessibility, sequence variation, and gene expression with new technology
Host: Erich Grotewold
About the Speaker
University: University of Washington
Research Interests: "Our research focuses on two related fields: the genetic architecture of complex traits and the role of gene regulation and protein folding in generating heritable phenotypic variation. We advance complex trait genetics by ascertaining uncharacterized sequence variation and by resolving the relative importance of additive variation and epistasis in complex traits. Lastly, to improve the genotype- phenotype map, we envision molecular markers, applicable in any organism, that predict the penetrance of genetic variants in a given individual."
"To advance our understanding of plant gene regulation, we build on our recent success in mapping the A. thaliana cis-regulatory landscape in response to heat and light, in specific cell types, and across divergent strains. Future projects emphasize the functional exploration of newly identified regulatory phenomena. Prompted by recent findings, we explore the role of prions as developmental switches in plants."