Ron Cook (Benning lab)
- Dec 10, 2019
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Date & Location: December 10, 2019, at 12p; Room 168 Plant Biology Building
Subject: Phosphatidic acid phosphatases in chloroplast lipid metabolism
Abstract: Chloroplast membranes are unique in that they are not primarily composed of phospholipids. Instead, galactolipids comprise over 75% of chloroplast membrane lipids, thereby minimizing the phosphate requirement of plants. The galactolipids are synthesized from diacylglycerol (DAG) at the chloroplast inner envelop membrane (IEM). DAG in itself is a product of the dephosphorylation of phosphatidic acid (PA) by enzymes known as PA phosphatases. PA is assembled in both the IEM and the endoplasmic reticulum (ER). While chloroplast-derived PA is known to be dephosphorylated at the IEM by PA phosphatases, it is unclear whether ER-derived PA is imported into the IEM for dephosphorylation by these same enzymes, or whether it is dephosphorylated prior to being imported as DAG. Current research on the chloroplast-localized PA phosphatases LPPγ, LPPε1, and LPPε2 seeks to address these gaps in our understanding of how plants convert phospholipids into galactolipids.
Speaker Lab: Dr. Christoph Benning