Director, MSU Foundation Professor, University Distinguished Professor
Departments: Biochemistry & Molecular Biology - Plant Biology
Research: Lipid Metabolism in Photosynthetic Organisms
Research in the Benning laboratory focuses on lipid metabolism in photosynthetic organisms. One area of particular interest is the assembly and maintenance of the photosynthetic membrane in plants and algae. The photosynthetic membrane contains a unique set of polar lipids. Their specific functions in photosynthesis, especially during dynamic conditions and under stress, are investigated by applying state-of-the-art phenotyping to Arabidopsis and Chlamydomonas lipid mutants.
Different membranes cooperate in the synthesis of lipid precursors needed for the assembly of the photosynthetic membrane. Thus, lipid biosynthetic enzymes and lipid transport mechanisms involving chloroplast envelope membranes are investigated in the model plant Arabidopsis using biochemical, cell biological, and molecular genetic approaches.
Photosynthetic organisms are exposed to a changing environment which can lead to stress inhibiting growth. Lipid remodeling in response to adverse temperatures or nutrient deprivation is an area of study in the Benning lab. Nutrient-deprived algae enter a state of cellular quiescence. Cell divisions cease and metabolism is redirected to accumulate storage lipids. The Benning laboratory is identifying factors governing cell division in response to the metabolic state of cells in single-celled algae. Approaches ranging from biochemistry, genetics, and systems biology to modeling are used to gain insights into this process with the goal to optimize algae for biofuel production.
- Ph.D. 1991, Michigan State University
- M.S. 1986, Albert-Ludwigs Universitaet, Freiburg, Germany
Now with Ph.D. in hand, former MSU-DOE Plant Research Laboratory (PRL) graduate student Yang-Tsung Lin is ready to continue his studies in algae as a postdoctoral researcher in Professor Sabeeha Merchant’s lab at UC Berkeley, beginning in July 2022.
Member of the Benning lab at the MSU-DOE Plant Research Laboratory (PRL) Drew Mitchell is a recipient of the 2022 Department of Microbiology & Molecular Genetics (MMG) Dietrich C. Bauer Scholarship Fund award.